| Modification (Engine) | Doors | Power (hp) | Type coupe | Seats | Start (year) | End (year) |
|---|---|---|---|---|---|---|
| E 350 4MATIC (272 Hp) | 5 | 272 | Combi | 5 | 2009 | 2013 |
| E 350 4MATIC BlueEFFICIENCY (272 Hp) | 4 | 272 | Sedan | 5 | 2009 | 2013 |
| E 350 4Matic (272 Hp) | 4 | 272 | Sedan | 5 | 2004 | 2009 |
| E 350 4Matic (272 HP) 7G-Tronic | 4 | 272 | Sedan | 5 | 2009 | 2013 |
| E 350 (272 Hp) | 4 | 272 | Sedan | 5 | 2004 | 2009 |
| E 350 4Matic (272 Hp) | 5 | 272 | Combi | 5 | 2004 | 2009 |
| E 350 (272 Hp) | 5 | 272 | Combi | 5 | 2004 | 2009 |